产品货号:
Z32098
中文名称:
CRK抗体
英文名称:
Anti-CRK Antibody (Clone#24C53)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CRK Antibody (Clone#24C53) |
指标别名 | Adapter molecule crk;CRK;CRKII;p38;Proto oncogene c Crk |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ICC/IF,IP,FCM |
基因名称 | CRK |
克隆号 | 24C53 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human CRKII |
实际分子量 | 38KD |
成分 | Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol,0.5mg/mL BSA. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CRK,also known as p38 or CRKII,is a protein that in humans is encoded by the CRK gene.This gene is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins.It is mapped to 17p13.3.The CRK protein participates in the Reelin signaling cascade downstream of DAB1.The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways,recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.Two alternative transcripts encoding different isoforms with distinct biological activity have been described. |
Uniprot ID | P46108 |
基因名全称 | v-crk avian sarcoma virus CT10 oncogene homolog |
蛋白名全称 | Adapter molecule crk |
推荐稀释比 | Western blot (WB) 1:500~2000 ICC/IF 1:50~1:200 IP 1:50 FCM 1:100 |
相关搜索:CRK抗体,CRK单抗,Anti-CRK Antibody (Clone#24C53)